Sagecast Archive
About this Sagecast: Dr. Michelle Dipp offers up an industry perspective on treating the symptoms of aging with drugs. She feels that the biggest challenges to the development of these medicines are scientific rather than rooted in policy, but she exudes confidence that we will tackle the problems of aging with pharmaceuticals in the near future.
About Dr. Dipp: Dr. Dipp works as a leader in development for Sirtris Pharmaceuticals. Read more about Dr. Dipp here.
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About This Sagecast: Dr. William Evans digs deeper into the issues keeping aging specific drugs from getting to the general public. It all boils down to a matter of policy and regulatory affairs.
About William Evans: Dr. Evans is the director of the Nutrition, Metabolism, and Exercise Laboratory in the Donald Reynolds Department of Geriatric Medicine at the University of Arkansas for Medical Sciences. Read more about Dr. Evans here.
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About this Sagecast: Dr. Larry Miller talks to Crossroads about the potential that pharmaceutical companies see in treating aging. He discusses whats on the horizon for treating the symptoms of aging, but he also cautions that there are several hurdles to overcome before these drugs can ever get to market.
About Larry Miller: Dr. Miller formerly lead business operations with the company Glaxo Smith Kline. To read more about Larry Miller, click here.
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About this Sagecast: Dr. Alexandre Kalache agrees that a compression of morbidity is occurring. He also endorses the idea that it is beneficial for society. He offered Crossroads his advice on the keys to compressing morbidity: health promotion and disease prevention.
About Alexandre Kalache: Dr. Kalache is a policy advisor to the president of the New York Academy of Medicine. Read more about Dr. Kalache here.
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About this Sagecast: Jim Fries, the mind behind the compression of morbidity theory, discussed what the research has been showing on the subject. He offered Crossroads his assesment as to whether or not a compression of morbidity is occurring across the spectrum and what this all actually means for society.
About James Fries: Dr. Fries is a research professor at the Stanford University School of Medicine. To read more about Dr. Fries, click here. To view his Sage Trading Card, click here.
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About this Sagecast: Research scientist Aubrey de Grey chatted with Sage Crossroads about his opposition to biomedical gerontology placing too much attention to a simple compression of morbidity. He offers his own opinions of how to refocus the research in this field in order to find what would be most beneficial for the population.
About Aubrey de Grey: Dr. de Grey is the chairman and chief science officer of the Methuselah Foundation. Read more about Dr. de Grey here.
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About this Sagecast: Dr. Stuart Kim's research has shown that aging may not be the cause of cellular damage, but rather it is due to developmental pathways that have gotten off track.
About Stuart Kim: Dr. Kim is a professor in the Department of Developmental Biology and Genetics at Stanford University School of Medicine. Read more about Dr. Kim here.
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About this Sagecast: Steven Austad is attempting to answer the question of why some species live for many, many years and other similar organisms have lifespans consisting of mere weeks.
About Dr. Austad: Dr. Austad is a researcher and professor at the University of Texas. Read more about him here.
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About this Sagecast: Daniel Perry discusses a few of the major theories of aging. He also tells us why it's important to understand these theories and how they impact aging research.
About Daniel Perry: Mr. Perry is the executive director of the Alliance for Aging Research. Read more about him here.
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About this Sagecast: Colin Farrelly answers the question, "Why should fighting aging matter?". He wants to silence the critics that say longevity science is not worthy of pursuing.
About Colin Farrelly: Dr. Farrelly is the Queen's National Scholar in the Department of Political Studies at Queen's University. Read more about Dr. Farrelly here.
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About this Sagecast: Dr. Leonard Guarente talks about discoveries in sirtruin biology, specifically that of resveratrol. Resveratrol, a natural compound that is found in red wine, may be the secret to unlocking a longer and healthier life.
About Dr. Guarente: Dr. Guarente, the founder of sirtruin biology, is the Novartis professor at the Massachusetts Institute of Technology. Read more about Dr. Guarente here.
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About this Sagecast: Dr. Ingram speaks his mind on the best ways to continue the pursuit for the elusive biomarkers of aging. He believes that expert roundtable discussions are essential to moving the field forward.
About Dr. Ingram: Dr. Ingram is a researcher with the Louisiana State University system. Read more about Dr. Ingram here.
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About this Sagecast: Dr. Richard Miller wants us to know how negative attitudes and lack of interest among researchers are having a large impact on the progression of the field. Until attitudes change and genuine interest picks up, we might not find any biomarkers of aging.
About Dr. Richard Miller: Dr. Miller is a professor and researcher at the University of Michigan. Read more about Dr. Miller here.
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About this Sagecast: Dr. Huber Warner also weighs in on the successes and failures of the NIA Biology of Aging program. His intuitions about the search for biomarkers are positive, and he has an optimistic outlook for the future of the field.
About Dr. Huber Warner: Dr. Huber Warner is a past program director for the NIA Biology of Aging Program. Read more about Huber Warner here.
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About this Sagecast: Dr. Richard Sprott confronts the question, "What did we learn from the National Institute of Aging's Biology of Aging program?"
About Dr. Richard Sprott: Dr. Sprott is the executive director of the Ellison Medical Foundation. Read more about Dr. Sprott here.
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